Principal Investigators
European Institute of Oncology
Department of Experimental Oncology
bruno.amati@ifom-ieo-campus.it
+39 0257 489824
Dr Amati has a long-standing interest in a transcription factor called Myc, which is also an important oncogene in human cancer. His group is particularly interested in the role of chromatin-modifying enzymes, such as histone acetyl- and methyl-transferases, in those biological responses.
Ecole Polytechnique Federale de Lausanne
Laboratory of Stem Cell Dynamic
yann.barrandon@epfl.ch
+41 21 6931633
Yann Barrandon, M. D., Ph. D, is a joint professor of Stem Cell Research and of Experimental Surgery at the Swiss Federal Institute of Technology Lausanne (EPFL) and the University of Lausanne (UNIL) and head of the Department of Experimental Surgery at the Lausanne University Hospital (CHUV).
University of Edinburgh
Institute for Stem Cell Research
c.blackburn@ed.ac.uk
+44 (0)1316 505843
Dr Blackburn’s research focuses on development of the thymus. The thymus plays a central role in the development of the body’s immune system as it is the main site in which T cells are generated. Dr Blackburn’s lab recently identified a population of progenitor/stem cells in mice that, on transplantation, is sufficient to generate a fully functional thymus.
Pasteur Institute
Department of Developmental Biology
margab@pasteur.fr
+33 1 4568 8477
Professor Buckingham's laboratory studies the formation of skeletal muscle. Their work focusses on the genes that regulate the entry of cells into the myogenic programme. Manipulation of these genes in the mouse gives new insight into their role in the specification, proliferation and survival of skeletal muscle stem cells. The introduction of genetic markers makes it possible to isolate such cells from different sources and to examine their therapeutic potential.
University of Milan
Department of Pharmacological Sciences and Center of Excellence on Neurodegenerative Diseases
elena.cattaneo@unimi.it
+39(0) 250318333
Professor Cattaneo has expertise in studying the biology of stem and progenitor cells derived from the developing brain, and the underlying mechanisms of Huntington's disease.
University of Edinburgh
Edinburgh Research and Innovation Ltd
ichambers@ed.ac.uk
+44 (0)131 6517242
Dr Ian Chambers’ line of research studies the molecules that direct self-renewal of undifferentiated ES cells. We are particularly interested in the role of the transcription factor Nanog, which we isolated through a functional screen for molecules capable of directing ES cell self-renewal in the absence of the otherwise obligatory LIF signal.
Netherlands Institute for Developmental Biology
Hubrecht Institute
clevers@niob.knaw.nl
+31 30 212 1831
Prof Hans Clevers’ research group studies TCF factors, mediators of Wnt signaling in development and cancer. His group has shown in frogs (4), flies (7) and worms (11) that upon Wingless/Wnt signaling, ß-catenin associates with nuclear TCFs and contributes a trans-activation domain to the resulting bipartite transcription factor. In the absence of Wnt signaling, we found that Tcf factors associate with proteins of the Groucho family of transcriptional repressors to repress target gene transcription.
San Raffaele, Milan
Developmental Neurogenetics Unit
g.consalez@hsr.it
+39 (0)2264 34838
Giacomo Consalez is a developmental neurobiologist at the San Raffaele Scientific Institute in Milan. His lab is focusing on cerebellar neurogenesis and development. The lab uses the mouse as a model system and, more recently, has made use of Neural Stem (NS) cells to characterize regulatory pathways of relevance in developmental neurogenesis. The group, that interacts closely with Elena Cattaneo's lab at the University of Milan, is interested in developing and utilizing new technologies to perform functional screens in NS cells, looking for factors affecting self renewal and neuronal type specification.
Medical Research Council
MRC Molecular Haematology Unit
tenver@gwmail.jr2.ox.ac.uk
+44 (0)1865 222141
Professor Tariq Enver leads the research at the MRC Molecular Haematology Unit at Oxford. His work involves attempting to understand the molecular events associated with the self-renewal and unilineage commitment of haematopoietic stem cells, and what goes wrong in leukemia.
Lund University / John Radcliffe Hospital, Oxford
Lund Strategic Centre for Stem Cell Biology and Cell Therapy / The Weatherall Institute of Molecular Medicine
stenj@gwmail.jr2.ox.ac.uk
+44 (0)1865 222425
Professor Sten Eirik Jacobsen is head of the research program which is focused on identifying molecular mechanisms governing stem cell fate decisions, and lineage development within the hematopoietic system.
Netherlands Cancer Institute
Division of Molecular genetics
j.jonkers@nki.nl
+31 20 512 2000
Dr. Jos Jonkers’ research group studies the genetic basis of human breast cancer, using advanced mouse models for p53-induced breast cancer, BRCA1- and BRCA2- associated hereditary breast cancer, and E-cadherin mutated invasive lobular carcinoma. These models are used for both basic and translational research, including studies to investigate the role of tumor initiating cells in tumor relapse, tumor metastasis and therapy resistance.
IMBA - Institute of Molecular Biotechnology
Asymmetric cell division and proliferation control in Drosophila
juergen.knoblich@imba.oeaw.ac.at
+43 1790 44 4800
Jürgen Knoblich is a senior scientist at the Institute of Molecular Biotechnology (IMBA) in Vienna. After graduating in biochemistry from the University of Tübingen, he pursued his Ph.D. in the laboratory of Christian Lehner at the Max Planck Institute, where he studied the role of cyclin proteins in cell-cycle progression in Drosophila. For his postdoc, he joined the laboratory of Lily and Yuh Nung Jan at University of California San Francisco to analyse the mechanisms of asymmetric cell division. In 1997, he became a junior group leader at the Institute of Molecular Pathology in Vienna and joined IMBA in 2004.
Karolinska Institute
Department of Cell and Molecular Biology
urban.Lendahl@ki.se
+46 852 48 7323
Urban Lendahl is professor in Genetics at the Department of Cell and Molecular Biology (CMB) at Karolinska Institute, Stockholm.
University of Cambridge
Cambridge Centre for Proteomics
ksl23@mole.bio.cam.ac.uk
+44 (0)1223 760255
Dr. Kathryn Lilley is director of the Cambridge Centre for Proteomics which is based in the Cambridge Systems Biology Centre, Department of Biochemistry, University of Cambridge. Her interests centre on developing methods for quantitative proteomics, phosphoproteomics and methods for tracking changes in sub-cellular localization of the proteome in response to cell signalling events.
University of Leipzig
Institute for Medical Informatics, Statistics and Epidemiology
markus.loeffler@imise.uni-leipzig.de
+49 341 971 6100
Professor Loeffler is Director of the Institute for Medical Informatics, Statistics and Epidermiology (IMISE), and Director of The Interdisciplinary Centre for Bioinformatics (IZBI). He is also Scientific Director of the Coordination Centre for Clinical Trials, Leipzig (KKSL). His research interests include Systems Biology of regenerative tissues and clinical trial research.
Ecole Polytechnique Federale de Lausanne
Swiss Institute for Experimental Cancer Research
Freddy.Radtke@epfl.ch
+41 21692.5964/5987
Prof Freddy Radtke is the Associate Professor in the School of Life Sciences at the Ecole Polytechnique Federale de Lausanne. His research is focused on the molecular mechanisms controlling homeostasis of self-renewing organs and their dysregulation during tumorigenesis.
AVISO-Trade GmbH
AndreRichter@aviso-trade.de
+49 (0) 364148200
After studying at the University of Rostock, André Richter has channelled his interests in cell biology, molecular biology and infectious diseases into a successful career in technical sales. Working in the area of molecular analytics he was a product specialist on JPK Instruments/nAmbition’s automatic force spectroscope. He continues to combine his work in sales with involvement in product development for AVISO.
University of Leipzig
Faculty of Medicine/Institute for Medical Informatics, Statistics and Epidemiology
ingo.roeder@imise.uni-leipzig.de
+49(0) 3419716111
Dr. Roeder is leader of the research group "DYNAmic Modeling of Stem Cell Organization" at the Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig and guest fellow at the Department of Computing, Goldsmiths, University of London. Dr. Roeder's research focus is the theoretical analysis of stem cell organization using system biological approaches such as mathematical modelling and computer simulation. Particularly, he is interested in the anlysis of stem cell fate decisions and of individual stem cell clone dynamics.
University of Cambridge
Wellcome Trust Centre for Stem Cell Research
ags39@cscr.cam.ac.uk
+44 (0)1223 760 233
Professor Austin Smith has expertise in the field of mouse developmental biology and has pioneered key advances in the field of Embryonic Stem Cell research. As co-ordinator of EuroSyStem, Professor Smith will act as overall leader for the project, will chair the meetings of the Board of Directors and the Project Steering Committee, and be responsible for all communication with the Commission on contractual Matters.
Oxford Gene Technology
ed.southern@bioch.ox.ac.uk
+44 (0)1865 856340
Professor Edwin Southern moved to Oxford in 1985 to take up the post of the Whitley Professorship of Biochemistry and in 1988 introduced methods of analysis using oligonucleotide arrays or 'DNA Chips'. He founded Oxford Gene Technology in 1995 to commercialise his work in the areas of DNA Microarrays. Ed retains a position at Oxford University as Professor of Biochemistry Emeritus.
Pasteur Institute
Department of Developmental Biology
shaht@pasteur.fr
+33 1 4061 3520
The research of Dr Tajbakhsh focuses on identifying and characterising skeletal muscle stem cells. A genetic approach in the mouse has been used to examine how skeletal muscle stem cells are born, and how they acquire their identity. In parallel, the roles of symmetric and asymmetric cell divisions are investigated as a mechanism for governing stem cell self-renewal and differentiation during embryonic development and in the adult. Genetically engineered fluorescent markers permit the isolation of these stem cells for cell based therapies, as well as their tracking using in vivo imaging to follow their fate.
University of Edinburgh
Edinburgh Research and Innovation Ltd
simon.tomlinson@ed.ac.uk
+44 (0)1316 517252
Dr Simon Tomlinson’s group uses bioinformatics to gain understanding of key molecular features of stem cell biology. His research group are building a database, StemDB, which will be used to store stem cell related information such as cell line information and expression profiling data.
Deutsches Krebsforschungszentrum (DKFZ)
Division of Cell Biology
a.trumpp@dkfz.de
+41 21 692 5817
Andreas Trumpp received his PhD in 1992 at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. In 1994 he moved to the USA where he did postdoctoral research in the laboratories of J. Michael Bishop and Gail R. Martin at the University of California at San Francisco (UCSF). He is now Head of the Division of Cell Biology at DKFZ.
Netherlands Cancer Institute
Division of Molecular Genetics
m.v.lohuizen@nki.nl
+31 (0) 20 512 2030
Maarten is the head of the Division of Molecular Genetics, NKI, and is a professor at Utrecht University Medical School. His group is are studying the mechanism of stable inherited epigenetic transcriptional repression by Polycomb-group (Pc-G) protein complexes, and the effects of deregulation of Pc-G genes on Homeobox gene expression, development, Cell cycle control and cancer formation.
University of Groningen
Department of Stem Cell Biology, University Medical Centre
g.de.haan@med.umcg.nl
+31 (0)50 363 2722
Gerald de Haan did his PHD at the University of Cologne, Germany and the University of Groningen, the Netherlands, under supervision of Prof. dr. Markus Loeffler and Dr William Nijhof, on vivo models addressing the issue of erythroid and myeloid lineage competition. As a post doctoral fellow he shifted his interest to the use of genetic mouse modules to map quantitative trait loci involved in various hematopietic stem cell traits. In addition he develop a strong interest in the ageing of hematopietic stem cells.
